How can we communicate the often complex scientific data in a concise and meaningful way?
The Ghent University Multidisciplinary Research Platform ‘From Nucleotides to Networks (N2N)’ is a center of excellence in state-of-the-art bioinformatical tools and methods with applications in the fields of Sustainable Agriculture and Successful Ageing, recognized worldwide as key challenges for a sustainable society.
It was established by Ghent University in 2011 as part of the strategic spearhead research policy plan promoting excellence in research, selected on the basis of the established expertise and the potential to become world leader in the field. Because of the growing importance of bioinformatics, computational biology, and systems biology in the life sciences, bioinformatics was one of the topics that were selected.
Monoallelic gene expression is typically initiated early in the development of an organism. Dysregulation of monoallelic gene expression has already been linked to several non-Mendelian inherited genetic disorders. In humans, DNA-methylation is... Read more
In 2009, the Van de Peer lab proposed a correlation between whole genome duplications in plants and the Cretaceous-Paleogene extinction event, the most recent mass extinction, which wiped out 70% of all life on earth, including the dinosaurs.... Read more
The HEK293 human cell lineage is widely used in cell biology and biotechnology. Here we use whole-genome resequencing of six 293 cell lines to study the dynamics of this aneuploid genome in response to the manipulations used to generate common... Read more